Role of Ubiquitin-Mediated Degradation System in Plant Biology
نویسندگان
چکیده
Ubiquitin-mediated proteasomal degradation is an important mechanism to control protein load in the cells. Ubiquitin binds to a protein on lysine residue and usually promotes its degradation through 26S proteasome system. Abnormal proteins and regulators of many processes, are targeted for degradation by the ubiquitin-proteasome system. It allows cells to maintain the response to cellular level signals and altered environmental conditions. The ubiquitin-mediated proteasomal degradation system plays a key role in the plant biology, including abiotic stress, immunity, and hormonal signaling by interfering with key components of these pathways. The involvement of the ubiquitin system in many vital processes led scientists to explore more about the ubiquitin machinery and most importantly its targets. In this review, we have summarized recent discoveries of the plant ubiquitin system and its involvement in critical processes of plant biology.
منابع مشابه
Synaptic Plasticity: Importance of Proteasome-Mediated Protein Turnover
The ubiquitin-proteasome system regulates protein degradation in every eukaryotic cell. Recent work has shown that protein turnover mediated by the ubiquitin-proteasome system plays a key role in synaptic plasticity.
متن کاملPlant Defence: A New Weapon In The Arsenal
Plants have evolved intricate defence mechanisms to cope with the wide array of microbial pathogens they encounter. The identification of Sgt1 as an essential component of R gene-mediated disease resistance suggests that the ubiquitin protein degradation pathway plays an important role in plant defence.
متن کاملFocus on ubiquitin in plant biology.
Ubiquitin and ubiquitin-like modifiers are small proteins that are covalently joined via their C-terminal carboxyl group to substrate proteins, often on a Lys residue, thereby modifying the stability, localization, or function of the target. Although ubiquitin is present in all eukaryotes, plants have an inordinate fondness for ubiquitin, as judged by the plethora of ubiquitin-protein ligases e...
متن کاملThe ubiquitin-proteasome system regulates plant hormone signaling.
Plants utilize the ubiquitin-proteasome system (UPS) to modulate nearly every aspect of growth and development. Ubiquitin is covalently attached to target proteins through the action of three enzymes known as E1, E2, and E3. The ultimate outcome of this post-translational modification depends on the nature of the ubiquitin linkage and the extent of polyubiquitination. In most cases, ubiquitinat...
متن کاملUbiquitin-mediated proteolysis in plant hormone signal transduction.
Being sessile organisms, plants usually have little control over their immediate growth environment. Responses to environmental and developmental factors need to be rapid and finely coordinated to trigger the necessary morphological and metabolic changes that ensure plant survival and growth. Many of these adaptive responses are mediated by plant hormones. Recent work has shown that ubiquitin-m...
متن کامل